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Rat Anti-Mouse CD4/L3T4-Alexa Fluor 488
- 348.35€
Product Details
| Alternative Names | |
| Alternative name | Anti-Rat Anti-Mouse CD4/L3T4-Alexa Fluor 488, Rat Anti-Murine CD4/L3T4-Alexa Fluor 488, Rattus norvegicus Anti-Mus musculus CD4/L3T4-Alexa Fluor 488, CD4/L3T4, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Rat Anti-Mouse CD4/L3T4-Alexa Fluor 488 is available on request. |
| Clone | |
| Clone | GK1.5 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Alexa Fluor 488 (AF488) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Rat |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG2b |
| Other gene names | |
| Other gene names | Cd4; Cd4; L3T4; Ly-4; N/A |
| Other names | |
| Other names | Cd4; Cd4; L3T4; Ly-4; N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | CD4/L3T4a, Mr 52 kDa CD4/L3T4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested.1,2 CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors.3-5 The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells.1,2 In vivo and in vitro treatment with the GK1.5 mAb effectively depletes CD4+ cells.7,8 The mAb also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.1,8-13 |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488) and Alexa Fluor 647 (AF647) conjugates are supplied as 0.1 mg in 0.2 mL of PBS/NaN3. Store Rat Anti-Mouse CD4/L3T4-Alexa Fluor 488 at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Rat Anti-Mouse CD4/L3T4-Alexa Fluor 488 is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
