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Hamster Anti-Mouse CD3e-Alexa Fluor 488
- 348.35€
Product Details
| Alternative Names | |
| Alternative name | Anti-Hamster Anti-Mouse CD3e-Alexa Fluor 488, Hamster Anti-Murine CD3e-Alexa Fluor 488, Hamster Anti-Mus musculus CD3e-Alexa Fluor 488, CD3e, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Hamster Anti-Mouse CD3e-Alexa Fluor 488 is available on request. |
| Clone | |
| Clone | 145-2C11 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Alexa Fluor 488 (AF488) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Armenian Hamster IgGk |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG |
| Other gene names | |
| Other gene names | N/A |
| Other names | |
| Other names | N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | Mouse CD3epsilon (Mr 25 kDa) CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL's. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death. 1-6 |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488) and Alexa Fluor 647 (AF647) conjugates are supplies as 0.1 mg in 0.2mL of PBS/NaN3. Store Hamster Anti-Mouse CD3e-Alexa Fluor 488 at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Hamster Anti-Mouse CD3e-Alexa Fluor 488 is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC) |
