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| Alternative Names | |
| Alternative name | Anti-Rat Anti-Mouse CD38-Pacific Blue, Rat Anti-Murine CD38-Pacific Blue, Rattus norvegicus Anti-Mus musculus CD38-Pacific Blue, CD38, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Rat Anti-Mouse CD38-Pacific Blue is available on request. |
| Clone | |
| Clone | 90 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Pacific Blue (PacBlu) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Rat |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG2a |
| Other gene names | |
| Other gene names | CD38; CD38; T10; cADPr hydrolase 1 |
| Other names | |
| Other names | CD38; CD38; T10; cADPr hydrolase 1 |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | CD38 (Mr 42-kDa), an immunoregulatory ectoenzyme Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR).1-3 It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice.4 It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-.5, 6 Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.4, 7 Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.2,5, 8 |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488), Alexa Fluor 647 (AF647) and Pacific Blue (PacBlu) conjugates are supplied as 0.1 mg in 0.2 mL PBS/NaN3. Store Rat Anti-Mouse CD38-Pacific Blue at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Rat Anti-Mouse CD38-Pacific Blue is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
