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| Alternative Names | |
| Alternative name | Anti-Mouse Anti-Human CD49d/VLA-4-UNLB, Murine Anti-Human CD49d/VLA-4-UNLB, Mus musculus Anti-Homo sapiens CD49d/VLA-4-UNLB, CD49d/VLA-4, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Mouse Anti-Human CD49d/VLA-4-UNLB is available on request. |
| Clone | |
| Clone | 7,2 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Purified (UNLB) Antibody |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Mouse |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG1 |
| Other gene names | |
| Other gene names | N/A |
| Other names | |
| Other names | N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Human |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | Human CD49d/VLA-4 CD49d, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha4 chain. CD49d associates noncovalently with CD29, the integrin beta1 subunit, to form the alpha4beta1 very late antigen-4 (VLA-4) heterodimer. Integrin alpha4 can also associate with integrin beta7 to form the alpha4beta7 heterodimer. It is expressed on most leukocytes, with the possible exception of neutrophils. VLA-4 mediates leukocyte binding to CD106/VCAM-1, and is involved in the migration of leukocytes from blood to tissue at sites of inflammation. VLA-4 can also provide a costimulatory signal to T cells for activation and proliferation. The alpha4beta7 integrin heterodimer is expressed on a small subpopulation of thymocytes, most lymph node T and B lymphocytes, NK cells and eosinophils. Integrin alpha4beta7 also binds to fibronectin and VCAM-1.1-4 |
| Storage and shipping | |
| Storage and shipping | The fluorescein (FITC), Alexa Fluor 488 (AF488), Alexa Fluor 647 (AF647), and Cyanine 5 (CY5) conjugates are supplied as 100 tests in 1.0 mL of PBS/NaN3. Store Mouse Anti-Human CD49d/VLA-4-UNLB at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Mouse Anti-Human CD49d/VLA-4-UNLB is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blot (WB) |
