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Rat Anti-Mouse CD54/ICAM-1-Pacific Blue
- 348.35€
Product Details
| Alternative Names | |
| Alternative name | Anti-Rat Anti-Mouse CD54/ICAM-1-Pacific Blue, Rat Anti-Murine CD54/ICAM-1-Pacific Blue, Rattus norvegicus Anti-Mus musculus CD54/ICAM-1-Pacific Blue, CD54/ICAM-1, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Rat Anti-Mouse CD54/ICAM-1-Pacific Blue is available on request. |
| Clone | |
| Clone | YN1/1.7.4 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Pacific Blue (PacBlu) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Rat |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG2b |
| Other gene names | |
| Other gene names | N/A |
| Other names | |
| Other names | N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | Mouse CD54/ICAM-1, Mr 95 kDa CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-gamma, IL-1, TNF-alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1. |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488), Alexa Fluor 647 (AF647), and Pacific Blue (PacBlu) conjugates are supplied as 0.1 mg in 0.2 mL of PBS/NaN3. Store Rat Anti-Mouse CD54/ICAM-1-Pacific Blue at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Rat Anti-Mouse CD54/ICAM-1-Pacific Blue is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
