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| Alternative Names | |
| Alternative name | Anti-Rat Anti-Mouse CD45R/B220-Pacific Blue, Rat Anti-Murine CD45R/B220-Pacific Blue, Rattus norvegicus Anti-Mus musculus CD45R/B220-Pacific Blue, CD45R/B220, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Rat Anti-Mouse CD45R/B220-Pacific Blue is available on request. |
| Clone | |
| Clone | RA3-6B2 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Pacific Blue (PacBlu) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Rat |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG2a |
| Other gene names | |
| Other gene names | N/A |
| Other names | |
| Other names | N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | B220 isoform of CD45, Mr 240 kDa CD45R/B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and, prior to the availability of anti-CD19 MAbs, was commonly used as a pan B-cell marker.1-5 It also reacts with certain activated T cells, as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells.1, 6 In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.7, 8 |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488), Alexa Fluor 647 (AF647), and Pacific Blue (PacBlu) conjugates are supplied as 0.1 mg in 0.2 mL of PBS/NaN3. Store Rat Anti-Mouse CD45R/B220-Pacific Blue at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Rat Anti-Mouse CD45R/B220-Pacific Blue is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunohistochemistry (IHC) |
