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Mouse Anti-Mouse CD45.2/Ly-5.2-Pacific Blue
- 348.35€
Product Details
| Alternative Names | |
| Alternative name | Anti-Mouse Anti-Mouse CD45.2/Ly-5.2-Pacific Blue, Murine Anti-Murine CD45.2/Ly-5.2-Pacific Blue, Mus musculus Anti-Mus musculus CD45.2/Ly-5.2-Pacific Blue, CD45.2/Ly-5.2, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Mouse Anti-Mouse CD45.2/Ly-5.2-Pacific Blue is available on request. |
| Clone | |
| Clone | 104 |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Pacific Blue (PacBlu) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | N/A |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG2a |
| Other gene names | |
| Other gene names | N/A |
| Other names | |
| Other names | N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | Mouse CD 45.2 (Leukocyte Common Antigen) The CD45 antigen is an essential regulator of leukocyte activation and development, and is now known to be a protein tyrosine phosphatase, e.g. CD45 is able to dephosporylate the Src family of protein kinases.1, 2 This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling and Fc receptor stimulation. 1, 2 The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685 and 1820) and as allelic forms CD45.1/Ly-5.1 and CD45.2/Ly-5.2. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. 3, 4 The monoclonal antibody 104 recognizes CD45 (Leukocyte Common Antigen) on all leukocytes of mouse strains expressing the CD45.2 allotype (e.g. A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488), Alexa Fluor 647 (AF647), and Pacific Blue (PacBlu) conjugates are supplied as 0.1 mg in 0.2 mL of PBS/NaN3. Store Mouse Anti-Mouse CD45.2/Ly-5.2-Pacific Blue at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Mouse Anti-Mouse CD45.2/Ly-5.2-Pacific Blue is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Fluorescence Microscopy |
