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Rat Anti-Mouse CD107a/LAMP-1-Alexa Fluor 488
- 348.35€
Product Details
| Alternative Names | |
| Alternative name | Anti-Rat Anti-Mouse CD107a/LAMP-1-Alexa Fluor 488, Rat Anti-Murine CD107a/LAMP-1-Alexa Fluor 488, Rattus norvegicus Anti-Mus musculus CD107a/LAMP-1-Alexa Fluor 488, CD107a/LAMP-1, N/A |
| Clonality | |
| Clonality | Information regarding the clonality of Rat Anti-Mouse CD107a/LAMP-1-Alexa Fluor 488 is available on request. |
| Clone | |
| Clone | 1D4B |
| Concentration | |
| Concentration | N/A |
| Form/Appearance | |
| Form/Appearance | Alexa Fluor 488 (AF488) Conjugate |
| Gene name | |
| Gene name | N/A |
| Gene name synonyms | |
| Gene name synonyms | N/A |
| Host organism | |
| Host organism | Rat |
| Immunoglobulin isotype | |
| Immunoglobulin isotype | IgG2a |
| Other gene names | |
| Other gene names | N/A |
| Other names | |
| Other names | N/A |
| Purification method | |
| Purification method | N/A |
| Species reactivity | |
| Species reactivity | Mouse |
| Specificity and cross-reactivity | |
| Specificity and cross-reactivity | Murine CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa) CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles.1 It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.2 CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.3 LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.4 |
| Storage and shipping | |
| Storage and shipping | The Alexa Fluor 488 (AF488) conjugate is supplied as 0.1 mg in 0.2 mL of PBS/NaN3. Store Rat Anti-Mouse CD107a/LAMP-1-Alexa Fluor 488 at +4 degrees Celsius. Temperature variations in the range +1 to +7 degrees Celsius are tolerable. Freezing of Rat Anti-Mouse CD107a/LAMP-1-Alexa Fluor 488 is NOT recommended. |
| Tested for | |
| Tested for | Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blot (WB), Immunoelectron Microscopy, Immunohistochemistry (IHC) |
